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10 Best Mexican Restaurants In Santa Ana

  • 10 restaurants
  • Santa Ana, California
  • Updated February 12, 2026

The 10 best Mexican restaurants in Santa Ana include Taqueria El Taquero Guzman, Casa Ramos, Los Grandes Originales, Rosa Madera, La Chiquita Restaurant, Tamales Irma, Tacompadre, Mariscos Los Portales, Marys Restaurant, and Perla Mexican Cuisine. Santa Ana is known for its Mexican food because of its deep specialization and authenticity, driven by the city's role as a cultural center for Orange County's Latino community. Signature dishes here include traditional al pastor, handmade tamales, and fresh mariscos. 

Mexican food in Santa Ana is widely available along major thoroughfares like Main Street and 1st Street, and within the historic downtown district. There are authentic and no-frills taquerias, specialized seafood kitchens, and contemporary dining rooms to choose from. Guests can experience the quick counter service at Los Grandes Originales or the sophisticated, high-energy atmosphere at Rosa Madera. A meal at a Mexican restaurant in Santa Ana costs between $5 and $70 per person.

Santa Ana's best Mexican restaurants are known for mastering specific culinary crafts, from the traditional art of the trompo al pastor to the homestyle preparation of handmade tamales. The best Mexican restaurant in Santa Ana is Taqueria El Taquero Guzman, distinguished by its authentic trompo-cooked al pastor, unwavering focus on traditional taco craft, and status as a community staple. Los Grandes Originales serves some of the best Santa Ana Mexican food with its famous, massive burritos. Rosa Madera provides a fine-dining experience with its creative and chef-driven menu, along with a dedicated vegan menu. 

The top Mexican restaurants in Santa Ana are listed below.

  1. Casa Ramos 1
    Casa Ramos is a family-owned restaurant in Santa Ana that serves a wide menu of traditional, homestyle Mexican dishes. The establishment provides a casual, friendly atmosphere and is known for its generous portions and classic recipes.
    Item Prices
    787
    Average Item Price
    $15.54
    More about Casa Ramos

    Type of Restaurant:

    Casual Dining

    Type of Food:

    Traditional Mexican

    Signature Dishes:

    EnmoladasCasa FajitasCarnitas Burrito 

    Casa Ramos signature dishes:: EnmoladasCasa FajitasCarnitas Burrito 

    Location:

    1717 S Main St, Santa Ana, CA 92707, United States

    Special Feature:

    The restaurant is well-regarded for its molcajete, a large, sizzling volcanic stone bowl filled with grilled meats, cactus, and cheese.

    What Makes It Special:

    Casa Ramos is a reliable neighborhood spot known for its consistent, comforting food and a welcoming environment suitable for family meals.

    What Sets It Apart:

    Its focus on a broad and classic menu, executed with homestyle care, makes it a go-to destination for a traditional and satisfying sit-down Mexican dinner.

    Operating Hours:

    Tuesday–Thursday: 11:00 AM – 8:00 PMFriday: 11:00 AM – 9:00 PMSaturday: 10:00 AM – 9:00 PMSunday: 9:00 AM – 7:00 PMMonday: Closed

    Price:

    $10 to $20 per person

    Casa Ramos Menu Prices
  2. La Chiquita Restaurant 2
    La Chiquita Restaurant is a long-standing, family-owned eatery in Santa Ana that serves authentic, homestyle Mexican comfort food. The restaurant is a small, unpretentious spot cherished by the local community for its traditional recipes.
    Item Prices
    335
    Average Item Price
    $9.65
    More about La Chiquita Restaurant

    Type of Restaurant:

    Casual Eatery

    Type of Food:

    Traditional Mexican

    Signature Dishes:

    Ground Beef TacoCheese EnchiladaChile Verde Burrito With Pork

    La Chiquita Restaurant signature dishes:: Ground Beef TacoCheese EnchiladaChile Verde Burrito With Por...

    Location:

    906 E Washington Ave, Santa Ana, CA 92701, United States

    Special Feature:

    The restaurant has been operating for decades, establishing itself as a historic and beloved neighborhood institution.

    What Makes It Special:

    La Chiquita is known for its consistent, high-quality homestyle cooking that tastes like a traditional family meal, particularly its weekend menudo.

    What Sets It Apart:

    Its enduring legacy and its unwavering focus on simple, perfectly executed comfort food make it a pure and authentic piece of Santa Ana's culinary history.

    Operating Hours:

    Monday, Tuesday–Thursday, Saturday: 11:30 AM – 8:00 PMFriday: 11:30 AM – 8:30 PMSunday: Closed

    Price:

    $10 to $20 per person

    La Chiquita Restaurant Menu Prices
  3. Tacompadre 3
    Pizza Mexican Latin American New Mexican
    Tacompadre is a modern, fast-casual taqueria in Santa Ana offering a contemporary take on Mexican street food. The restaurant is known for its high-quality ingredients, creative taco combinations, and a vibrant, trendy atmosphere.
    Item Prices
    16
    Average Item Price
    $7.49
    More about Tacompadre

    Type of Restaurant:

    Fast-Casual, Taqueria

    Type of Food:

    Modern Mexican, Tacos

    Signature Dishes:

    BurritosLoaded FriesQuesotacos

    Tacompadre signature dishes:: BurritosLoaded FriesQuesotacos

    Location:

    515 N Main St suite A, Santa Ana, CA 92701, United States

    Special Feature:

    The taqueria is famous for its crispy, cheesy quesatacos, a modern take on birria tacos served with a rich consommé for dipping.

    What Makes It Special:

    Tacompadre is a popular spot for its fresh, high-energy approach to the taqueria experience, blending authentic flavors with a modern, social environment.

    What Sets It Apart:

    Its focus on trendy, high-quality items like quesatacos and its modern, efficient service model make it a distinct and popular contemporary taqueria.

    Operating Hours:

    Tuesday–Thursday: 10:00 AM – 9:00 PMFriday: 10:00 AM – 1:00 AMSaturday: 11:00 AM – 1:00 AMSunday: 11:00 AM – 8:00 PMMonday: Closed

    Price:

    $10 to $20 per person

    Tacompadre Menu Prices
  4. Perla Mexican Cuisine 4
    Perla Mexican Cuisine is a casual, family-run restaurant in Santa Ana that offers a broad menu of classic Mexican dishes. The establishment provides a relaxed and friendly atmosphere for diners to enjoy traditional combination plates and house specialties.
    Item Prices
    37
    Average Item Price
    $13.14
    More about Perla Mexican Cuisine

    Type of Restaurant:

    Casual Dining

    Type of Food:

    Traditional Mexican

    Signature Dishes:

    Ceviche TrioVeggie FajitasGuacamole

    Perla Mexican Cuisine signature dishes:: Ceviche TrioVeggie FajitasGuacamole

    Location:

    400 W 4th St, Santa Ana, CA 92701, United States

    Special Feature:

    The restaurant is located in the historic downtown Santa Ana area, making it a convenient spot for shoppers and visitors.

    What Makes It Special:

    Perla is a dependable downtown restaurant known for its generous portions, friendly service, and a comprehensive menu of well-prepared traditional food.

    What Sets It Apart:

    Its role as a straightforward, family-friendly restaurant in the heart of the downtown district makes it a reliable choice for a classic Mexican meal.

    Operating Hours:

    Tuesday–Thursday: 11:00 AM – 10:00 PMFriday–Saturday: 11:00 AM – 11:00 PMSunday: 10:00 AM – 4:00 PMMonday: Closed

    Price:

    $20 to $30 per person

    Perla Mexican Cuisine Menu Prices
  5. Taqueria El Taquero Guzman 5

    5. Taqueria El Taquero Guzman

    Taqueria El Taquero Guzman is a classic, no-frills taqueria in Santa Ana that focuses on serving authentic Mexican street tacos. The establishment is a simple, counter-service spot known for its traditional meat preparations and flavorful salsas.
    More about Taqueria El Taquero Guzman

    Type of Restaurant:

    Taqueria

    Type of Food:

    Mexican Street Food, Tacos

    Signature Dishes:

    QuesadillaCalifornia BurritoGorditas

    Taqueria El Taquero Guzman signature dishes:: QuesadillaCalifornia BurritoGorditas

    Location:

    925 W Warner Ave, Santa Ana, CA 92707, United States

    Special Feature:

    The taqueria is known for its authentic al pastor, marinated pork cooked on a vertical spit (trompo) and carved to order.

    What Makes It Special:

    The eatery is a go-to for a genuine street taco experience, celebrated for its high-quality meats, simple preparation, and authentic flavors.

    What Sets It Apart:

    Its unwavering dedication to the traditional taqueria craft, especially its trompo al pastor, distinguishes it as a purist's choice for authentic street food.

    Operating Hours:

    Monday–Sunday: 8:00 AM – 10:00 PM

    Price:

    $10 to $20 per person

  6. Los Grandes Originales 6

    6. Los Grandes Originales

    Los Grandes Originales is a popular, no-frills taqueria in Santa Ana known for its large, well-stuffed burritos and authentic Mexican street food. The establishment operates with a quick-service model in a casual, bustling setting.
    More about Los Grandes Originales

    Type of Restaurant:

    Taqueria

    Type of Food:

    Mexican Street Food

    Signature Dishes:

    TacoMenudoDorados

    Los Grandes Originales signature dishes:: TacoMenudoDorados

    Location:

    3522 W 1st St, Santa Ana, CA 92703, United States

    Special Feature:

    The taqueria is famous for its "Grande" burrito, a very large burrito packed with a choice of meat, beans, rice, and toppings.

    What Makes It Special:

    Los Grandes Originales is a local favorite for its generously sized portions, flavorful meats, and affordable prices, making it a staple for a quick and filling meal.

    What Sets It Apart:

    Its reputation for massive, high-quality burritos distinguishes it as a legendary spot in Santa Ana's street food scene.

    Operating Hours:

    Monday–Thursday: 8:00 AM – 8:00 PMFriday: 7:00 AM – 8:00 PMSaturday: 7:00 AM – 9:00 PMSunday: 7:00 AM – 8:00 PM

    Price:

    $10 to $20 per person

  7. Rosa Madera 7

    7. Rosa Madera

    Rosa Madera is an upscale, modern Mexican restaurant and bar in Santa Ana. The establishment features a stylish, chic interior, a sophisticated craft cocktail program, and a menu of contemporary, chef-driven Mexican dishes.
    More about Rosa Madera

    Type of Restaurant:

    Upscale Casual, Fine Dining

    Type of Food:

    Modern Mexican

    Signature Dishes:

    Birria ChimichangasMolcajeteLengua En Salsa Verde

    Location:

    2158 S Bristol St, Santa Ana, CA 92704, United States

    Special Feature:

    The restaurant has a high-energy, social atmosphere with a focus on its extensive bar program, featuring tequila, mezcal, and signature cocktails.

    What Makes It Special:

    Rosa Madera is known for its elevated, contemporary approach to Mexican cuisine, blending high-quality ingredients with creative presentations in a vibrant, stylish setting.

    What Sets It Apart:

    Its fusion of a gourmet, modern menu with a trendy, nightlife-oriented lounge atmosphere makes it a distinct destination for a sophisticated social dining experience.

    Operating Hours:

    Monday–Thursday: 11:00 AM – 10:00 PMFriday: 11:00 AM – 12:00 AMSaturday: 10:00 AM – 12:00 AMSunday: 10:00 AM – 10:00 PM

    Price:

    $20 to $30 per person

  8. Tamales Irma 8

    8. Tamales Irma

    Tamales Irma is a small, specialized eatery in Santa Ana that is dedicated to making and selling traditional, handmade tamales. The menu is tightly focused on various types of tamales, available for individual purchase or by the dozen.
    More about Tamales Irma

    Type of Restaurant:

    Specialty Eatery, Tamaleria

    Type of Food:

    Tamales, Traditional Mexican

    Signature Dishes:

    Banana Leaf WrappedChicken TamalesRajas Con Queso

    Tamales Irma signature dishes:: Banana Leaf WrappedChicken TamalesRajas Con Queso

    Location:

    2016 S Flower St, Santa Ana, CA 92707, United States

    Special Feature:

    The establishment's primary and almost exclusive focus is on the craft of making authentic, homestyle tamales.

    What Makes It Special:

    Tamales Irma is a go-to destination for high-quality, traditional tamales, celebrated for its flavorful fillings and perfectly prepared masa.

    What Sets It Apart:

    Its specialization in a single, iconic Mexican dish allows for a level of quality and authenticity that distinguishes it as an expert in its craft.

    Operating Hours:

    Wednesday–Sunday: 6:15 AM – 10:30 AMMonday–Tuesday: Closed

    Price:

    $1 to $10 per person

  9. Mariscos Los Portales 9

    9. Mariscos Los Portales

    Mariscos Los Portales is a casual restaurant in Santa Ana that specializes in mariscos, or Mexican seafood dishes. The menu features a wide variety of fresh seafood cocktails, ceviches, grilled fish, and shrimp plates.
    More about Mariscos Los Portales

    Type of Restaurant:

    Casual Dining, Marisqueria

    Type of Food:

    Mexican Seafood (Mariscos)

    Signature Dishes:

    Shrimp TostadaChorizoCarne Asada Burrito

    Mariscos Los Portales signature dishes:: Shrimp TostadaChorizoCarne Asada Burrito

    Location:

    1400 W McFadden Ave Ste 5 Santa Ana, CA 92704

    Special Feature:

    The restaurant's extensive menu is dedicated almost entirely to fresh mariscos, offering a comprehensive selection of coastal Mexican cuisine.

    What Makes It Special:

    The eatery is a destination for authentic Mexican seafood, known for its fresh ingredients, generous portions, and vibrant, coastal flavors.

    What Sets It Apart:

    Its primary focus on mariscos distinguishes it from general Mexican restaurants, providing a specialized menu centered on the diverse seafood preparations of Mexico.

    Operating Hours:

    Monday–Thursday: 10:00 AM – 10:00 PMFriday–Sunday: 10:00 AM – 2:00 AM

    Price:

    $20 to $30 per person

  10. Marys Restaurant 10

    10. Marys Restaurant

    Marys Restaurant is a casual, family-owned eatery in Santa Ana serving a menu of authentic, homestyle Mexican dishes. The restaurant is a local favorite, known for its friendly service and traditional comfort food classics.
    More about Marys Restaurant

    Type of Restaurant:

    Casual Dining

    Type of Food:

    Traditional Mexican

    Signature Dishes:

    MenudoCarne AsadaCarnitas

    Marys Restaurant signature dishes:: MenudoCarne AsadaCarnitas

    Location:

    1819 S Main St, Santa Ana, CA 92707, United States

    Special Feature:

    The restaurant is well-regarded for its flavorful, slow-cooked meats, particularly its carnitas and birria de res.

    What Makes It Special:

    Marys is known for its consistent, high-quality homestyle cooking that delivers the authentic taste of a traditional Mexican kitchen.

    What Sets It Apart:

    Its focus on straightforward, perfectly executed comfort food in a simple, welcoming setting makes it a reliable and beloved neighborhood destination.

    Operating Hours:

    Monday, Tuesday–Friday: 9:00 AM – 9:00 PMSaturday: 9:00 AM – 9:00 PMSunday: 8:00 AM – 9:00 PM

    Price:

    $10 to $20 per person

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